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KMID : 0363219960340010071
Korean Journal of Dermatology
1996 Volume.34 No. 1 p.71 ~ p.77
Study of the Minimal Erythema Dose and Minimal Melanogenic Dose of UVA-1 and Minimal Phototoxic Dose of UVA-1 and UVA-2 in Young Adult Koreans


Chae Young-Soo

Abstract
Background :
@EN Minimal erythema dose(MED), minimal melanogenic dose (MMD0 and minimal phototoxic dose (MPD) of UVA-1 in Koreans has not been determined, although MED and MMD of UVB and MPD of UVA-2 in Kor have been reported.
@ES Objective :
@EN This study was done to measure the MED and MMDs including minimal immediate tanning dose(MITD) and minimal delayed tanning dose(MDTD) of UVA-1 radiation and compare the MPD of UVA-1 with that of UVA-2.
@ES Methods :
@EN In this study, a metal halide lamp (SUPUVASUN 3000) and a fluorescent blacklight lamp (Philips TL 20W/09N UVA lamp) were used as the UVA-1 and UVA-2 light sources, respectively. After the determining of Fitzpatrick's skin phototypes, the back
skins
of young adults were irradiated and the MED, MITD and MDTD of UVA-1 were assessed at 24 hours, 1 hour, and 7 days after irradiation, respectively. The minimal doses of phototoxic reaction, which was induced by oral 8-MOP plus UVA-1 or UVA-1 were
assessed visually 72 hours after irradiation.
@ES Results :
@EN MED was 61.20¡¾11.50J/cm2(mean¡¾S.D.). MITD and MDTD of UVA-1 were 48.00¡¾8.57J/cm2 and 65.30¡¾12.10J/cm2, respectively. MPDs of UVA-1 and UVA-2 were 14.88¡¾3.88J/cm2 and 4.40¡¾1.69J/cm2, respectively.
@ES Conclusion :
@EN In this study, the MED and MMD of UVA-1 radiation and the MPD of UVA-1 and UVA-2 radiation were measured in young adult Koreans. The MITD was less than the MED, and the MDTD was almost the same as the MED. The MPD of VUA-1 was three times
higher
than that of UVA-2. There were no significant correlations between the MEDs, MMDs or MPDs and the skin phototypes. (Kor J Dermatol 1996;34(1) : 71~77)
KEYWORD
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